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. 2018 Sep 20;11:157–165. doi: 10.2147/PGPM.S158401

Table 4.

The effects of amlodipine on 24-hour, daytime and nighttime blood pressure variability in patients with rs1045642 ABCB1 polymorphisms

CC (n=17)
CT (n=53)
TT (n=30)
Baseline 12 weeks Baseline 12 weeks Baseline 12 weeks
24-hour SBP variability (mmHg) 14.91±2.2 13.41±1.72 15.01±2.45 13.35±1.85 14.86±2.13 12.20±1.60*
24-hour DBP variability (mmHg) 13.45±2.21 12.53±1.94 13.38±2.31 11.87±1.93 13.12±2.20 11.31±1.78*
Daytime SBP variability (mmHg) 13.96±2.97 12.45±2.23 14.52±2.98 11.67±2.33* 14.48±2.92 11.45±2.13**
Daytime DBP variability (mmHg) 12.98±2.68 11.03±2.22 12.74±2.75 10.83±2.42* 12.67±2.56 10.78±2.0
Nighttime SBP variability (mmHg) 13.86±2.23 13.01±2.18 13.59±1.93 12.75±2.32 13.39±1.87 12.51±2.16**
Nighttime DBP variability (mmHg) 11.88±1.94 11.05±2.97 12.41±1.83 10.54±2.36 11.0±1.67 10.47±2.09

Notes: Data are reported as mean ± SD.

*

P<0.05;

**

P<0.01.