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Adverse effects frequency in patients with rs1045642 ABCB1 gene polymorphisms undergoing amlodipine therapy
| rs1045642 | Adverse effect | Patients
|
Total per genotype, N (%) | Intergroup differences, Mann–Whitney U test, P-value | |
|---|---|---|---|---|---|
| N | % | ||||
| CC (n=17) | Edema | 5 | 29.4 | 6 (35.3) | CC vs CT, P=0.05 |
| Hyperemia | 1 | 5.9 | CC vs TT, P=0.05 | ||
| TT (n=30) | Edema | – | – | 2 (6.7) | CT vs TT, P=0.06 |
| Hyperemia | 2 | 6.7 | ANOVA, P=0.05 | ||
| CT (n=53) | Edema | 3 | 5.7 | 6 (11.3) | |
| Hyperemia | 3 | 5.7 | |||
