Table I.
Patient Characteristics, Surgery Details, Treatment Modalities and Patient Outcome (Hemoadsorption Group)
| Case | Age | Gender | BMI | Diagnosis | Microbiological findings | Operation procedure | Emergency | Euro SCORE II | CPB time (min) | X clamp time (min) | CytoSorb treatment time (min) | APACHE II postop | APACHE II 24h postop | Mechanical ventilation (days) | ECMO (days) | CRRT (days) | Hydrocortisone | ICU LOS (d) | ICU survival | Hospital survival |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 43 | M | 20.7 | AV Endocarditis | Staph. aureus | Re-Re ARR, Mechanoconduit | No | 18.96 | 253 | 151 | 253 | 1 | 2 | No | 12 | Yes | Yes | |||
| 2 | 73 | F | 24.8 | AV Endocarditis | Streptococcus mitis/cristatis | Re-AVR | No | 31.14 | 114 | 69 | 115 | 33 | 28 | 1 | No | 7 | Yes | Yes | ||
| 3 | 75 | F | 20.8 | AV Endocarditis | Bio-Conduit ARR, CABG | Yes | 96.73 | 445 | 250 | 445 | 46 | 1 | 1 | No | 1 | No | No | |||
| 4 | 67 | M | 21.3 | AV Endocarditis | Abiotropha defectiva | AVR, abscess removal, CABG-RCA | Yes | 12.75 | 138 | 100 | 138 | 26 | 14 | 1 | No | 7 | Yes | Yes | ||
| 5 | 75 | M | 28.7 | AV Endocarditis | Staph.aureus | AVR | Yes | 4.96 | 71 | 49 | 72 | 1 | No | 9 | Yes | Yes | ||||
| 6 | 37 | M | 36.0 | AV Endocarditis | Staph. aureus, Stertococcus pyogenes | AVR | Yes | 16.68 | 112 | 78 | 112 | 24 | 24 | 12 | Yes | 19 | Yes | Yes | ||
| 7 | 52 | M | 26.5 | MV + AV Endocarditis | Streptococcus mitis | MVR, AVR, ARRec, SCAE | No | 9.01 | 200 | 145 | 200 | 1 | Yes | 11 | Yes | Yes | ||||
| 8 | 69 | F | 49.5 | MV Endocarditis | Staph. aureus | MVR | Yes | 64.18 | 115 | 70 | 115 | 32 | 26 | No | 32 | No | No | |||
| 9 | 62 | M | 32.3 | MV Endocarditis | Streptococcus viridans | MVR | Yes | 48.24 | 171 | 107 | 142 | 31 | 21 | 2 | 3 | Yes | 6 | Yes | Yes | |
| 10 | 75 | M | 25.1 | MV + AV Endocarditis | Streptococcus mitis | AVR, MVR | Yes | 5.22 | 138 | 104 | 138 | 24 | 12 | 1 | No | 3 | Yes | Yes | ||
| 11 | 75 | F | 22.8 | AV Endocarditis | AVR | Yes | 9.62 | 88 | 60 | 88 | 30 | 15 | 1 | No | 4 | Yes | Yes | |||
| 12 | 64 | M | 26.9 | MV Endocarditis | Streptococcus agalactiae | MVR | Yes | 2.21 | 117 | 90 | 116 | 28 | 20 | 2 | No | 4 | Yes | Yes | ||
| 13 | 33 | M | 25.7 | TK Endocarditis | Staph. aureus, fungi | MICTKR | No | 4.43 | 101 | 61 | 102 | 31 | 17 | 1 | No | 5 | Yes | Yes | ||
| 14 | 38 | M | 19.8 | MV Endocarditis | Streptococcus agalactiae | MIC MVR | Yes | 6.2 | 109 | 75 | 91 | 33 | 20 | 1 | No | 4 | Yes | Yes | ||
| 15 | 77 | F | 30.1 | MV Endocarditis | Streptococcus bovis | MVR | Yes | 53.17 | 122 | 89 | 122 | 37 | 33 | 4 | 3 | Yes | 4 | No | No | |
| 16 | 60 | M | 30.0 | AV Endocarditis | AVR, MKR, TKR, RFA | Yes | 12.83 | 204 | 145 | 205 | 32 | 31 | 2 | 4 | Yes | 6 | Yes | Yes | ||
| 17 | 58 | M | 28.4 | MV Endocarditis | Streptococcus dysgalactiae | MVR, 2x CABG | Yes | 12.03 | 132 | 90 | 133 | 30 | 12 | 1 | No | 6 | Yes | Yes | ||
| 18 | 79 | F | 26.8 | MV Endocarditis | Streptococcus mitis | MVR | No | 3.99 | 66 | 45 | 64 | 28 | 18 | 3 | No | 4 | Yes | Yes | ||
| 19 | 62 | F | 27.7 | MV Endocarditis | Staph. aureus | MVR | Yes | 31.46 | 141 | 83 | 141 | 33 | 28 | 7 | 6 | Yes | 13 | Yes | Yes | |
| 20 | 73 | M | 23.5 | AV Endocarditis | Propionibacterium | AVR | No | 4.15 | 101 | 67 | 102 | 32 | 11 | 1 | No | 4 | Yes | No | ||
| 21 | 30 | M | 26.2 | AV Endocarditis | Staph. aureus | Re-AVR, TKE, VA ECMO | Yes | 31.69 | 280 | 129 | 282 | 30 | 30 | 2 | 2 | 1 | Yes | 2 | No | No |
| 22 | 76 | F | 29.3 | MV Endocarditis | Enterococcus faecalis | MVR | No | 74.69 | 159 | 69 | 160 | 33 | 30 | 8 | 4 | 1 | Yes | 8 | No | No |
| 23 | 57 | M | 27.1 | MV Endocarditis | Streptococcus agalactiae | MVR | Yes | 33.1 | 128 | 95 | 128 | 27 | 2 | 3 | Yes | 11 | Yes | Yes | ||
| 24 | 51 | F | 23.4 | AV Endocarditis | Streptococcus mitis | AVR, SCAE | Yes | 4.49 | 224 | 161 | 224 | 25 | 14 | 1 | No | 3 | Yes | Yes | ||
| 25 | 56 | M | 27.0 | AV Endocarditis | Staphylococcus aureus | bio Bentall, CABG, SCAE | No | 9.62 | 340 | 257 | 340 | 22 | 10 | 8 | No | 8 | Yes | Yes | ||
| 26 | 37 | M | 25.0 | AV Endocarditis | Streptokokken | Bentall OP, SCAE, abscess removal | No | 9.01 | 180 | 132 | 180 | 2 | No | 5 | Yes | Yes | ||||
| 27 | 59 | M | 24.6 | AV Endocarditis | Staph aureus | Re-AVR, RFA, LAA closure | No | 60.49 | 128 | 74 | 128 | 30 | 23 | 3 | 2 | Yes | 3 | Yes | No | |
| 28 | 48 | M | 23.4 | AV Endocarditis | Enterococcus faecalis | mAVR, mMVR, SCAE | Yes | 11 | 148 | 126 | 148 | 30 | 16 | 1 | No | 4 | Yes | Yes | ||
| 29 | 67 | F | 34.5 | MV + AV Endocarditis | RE AVR, MVR, ARR | No | 50.07 | 302 | 210 | 302 | 36 | 33 | 2 | 2 | 2 | Yes | 2 | No | No | |
| 30 | 60 | F | 44.5 | AV Endocarditis | Staph. aureus | Re-AVR | No | 22.23 | 125 | 84 | 125 | 32 | 13 | 3 | No | 6 | Yes | Yes | ||
| 31 | 77 | M | 23.7 | AV Endocarditis | Enterococcus faecalis | AVR, TKR, RFA, VA ECMO | Yes | 78.23 | 208 | 114 | 208 | 39 | 36 | 7 | 2 | 7 | Yes | 7 | No | No |
| 32 | 51 | M | 30.5 | AV Endocarditis | Streptococcus sanguinis | AVR, SCAE | Yes | 16.17 | 117 | 94 | 116 | 32 | 29 | 1 | No | 5 | Yes | Yes | ||
| 33 | 46 | M | 29.3 | AV Endocarditis | Staph. aureus | AVR | No | 62.96 | 157 | 87 | 157 | 5 | 5 | 5 | No | 5 | No | No | ||
| 34 | 56 | M | 22.6 | AV Endocarditis | Streptococcus agalactiae | AVR | No | 2.15 | 90 | 61 | 90 | 26 | 10 | 1 | No | 3 | Yes | Yes | ||
| 35 | 61 | M | 26.6 | AV prothesis Endocarditis | Re-AVR | No | 5.2 | 134 | 96 | 134 | 19 | 5 | 1 | No | 4 | Yes | Yes | |||
| 36 | 68 | M | 39.2 | AV Endocarditis | AVR | Yes | 5.67 | 82 | 54 | 82 | 3 | 3 | No | 4 | Yes | Yes | ||||
| 37 | 70 | M | 33.8 | AV Endocarditis | Streptococcus mitis | AVR | Yes | 28.3 | 110 | 73 | 110 | 1 | 3 | No | 10 | Yes | Yes | |||
| 38 | 61 | M | 16.9 | MV Endocarditis | No microbiologiacal finding | MVR, ACVB | Yes | 4.99 | 104 | 66 | 105 | 2 | No | 2 | Yes | Yes | ||||
| 39 | 75 | F | 39.7 | MV Endocarditis | Staphylococcus aureus | MVR | No | 55.76 | 131 | 87 | 132 | 31 | 19 | 3 | 3 | No | 11 | Yes | Yes |
ARR = aortic root replacement; AVR = aortic valve replacement; MVR = mitral valve replacement; ARRec = aortic root reconstruction; TKR = tricuspid valve replacement.