Table 1. Demography and predisposing factors of patients with cellulitis.
| All (n = 606) |
Good response (n = 520) |
Poor response (n = 86) |
P value | ||
|---|---|---|---|---|---|
| Demography & anthropometry | |||||
| Gender | Male | 314 (51.8%) | 275 (52.9%) | 39 (45.3%) | 0.19 |
| Female | 292 (48.2%) | 245 (47.1%) | 47 (54.7%) | ||
| Age (years) | 63.43 (61.85–65.05) | 62.70 (60.98–64.47) | 68.03 (64.25–72.03) | 0.03 | |
| Body mass index (kg/m2) | (n = 350) | 30.00 (29.25-30-77) | 29.90 (29.14–30.67) | 31.07 (27.73–34.81) | 0.5 |
| Predisposing factors / comorbidities* | |||||
| Prior cellulitis | Yes | 156 (25.7%) | 115 (22.1%) | 41 (47.7%) | <0.0001 |
| No | 450 (74.3%) | 405 (77.9%) | 45 (52.3%) | ||
| Episodes of prior cellulitis | (Only if prior cellulitis) | 1.72 (1.56–1.90) | 1.58 (1.42–1.76) | 2.19 (1.78–2.71) | 0.003 |
| Episodes of prior cellulitis | 0 | 450 (74.3%) | 405 (77.9%) | 45 (52.3%) | <0.0001 |
| 1 | 79 (13.0%) | 64 (12.3%) | 15 (17.4%) | ||
| 2 | 27 (4.5%) | 23 (4.4%) | 4 (4.7%) | ||
| 3 | 26 (4.3%) | 14 (2.7%) | 12 (14.0%) | ||
| 4 or more | 24 (4.0%) | 14 (2.7%) | 10 (11.6%) | ||
| Location of prior cellulitis | Same location | 143 (91.7%) | 104 (90.4%) | 39 (95.1%) | 0.5 |
| Other locations | 13 (8.3%) | 11 (9.6%) | 2 (4.9%) | ||
| Prior wounds | Yes | 332 (54.8%) | 289 (55.6%) | 43 (50.0%) | 0.3 |
| No | 274 (45.2%) | 231 (44.4%) | 43 (50.0%) | ||
| Type of wound | None | 274 (45.2%) | 231 (44.4%) | 43 (50.0%) | <0.0001 |
| Skin ulcer | 110 (18.2%) | 80 (15.4%) | 30 (34.9%) | ||
| Non-surgical trauma | 108 (17.8%) | 104 (20.0%) | 4 (4.7%) | ||
| Surgical | 34 (5.6%) | 26 (5.0%) | 8 (9.3%) | ||
| Animal bite | 12 (2.0%) | 11 (2.1%) | 1 (1.2%) | ||
| Injection | 11 (1.8%) | 11 (2.1%) | 0 (0.0%) | ||
| Arthropod bite | 11 (1.8%) | 11 (2.1%) | 0 (0.0%) | ||
| Others | 46 (7.6%) | 46 (8.8%) | 0 (0.0%) | ||
| Prior skin lesions | Yes | 182 (30.0%) | 146 (28.1%) | 36 (41.9%) | 0.01 |
| No | 424 (70.0%) | 374 (71.9%) | 50 (58.1%) | ||
| Diabetes | Yes | 153 (25.2%) | 126 (24.3%) | 27 (31.4%) | 0.16 |
| No | 453 (74.8%) | 394 (75.8%) | 59 (68.6%) | ||
| Venous insufficiency | Yes | 124 (20.5%) | 94 (18.1%) | 30 (34.9%) | 0.0003 |
| No | 482 (79.5%) | 426 (81.9%) | 56 (65.1%) | ||
| Prior deep venous thrombosis | Yes | 23 (3.8%) | 17 (3.3%) | 6 (7.0%) | 0.12 |
| No | 583 (95.9%) | 503 (96.7%) | 80 (93.0%) | ||
| Edema / lymphedema | Yes | 168 (27.7%) | 127 (24.4%) | 41 (47.7%) | <0.0001 |
| No | 438 (72.3%) | 393 (75.6%) | 45 (52.3%) | ||
| Heart failure | Yes | 101 (16.7%) | 82 (15.8%) | 19 (22.1%) | 0.15 |
| No | 505 (83.3%) | 438 (84.2%) | 67 (77.9%) | ||
| Obesity | Yes | 229 (37.8%) | 193 (37.1%) | 36 (41.9%) | 0.4 |
| No | 377 (62.2%) | 327 (62.9%) | 50 (58.1%) | ||
| Immunosuppression | Yes | 70 (11.6%) | 52 (10.0%) | 18 (20.9%) | 0.003 |
| No | 536 (88.4%) | 468 (90.0%) | 68 (79.1%) | ||
| Intravenous drug use | Yes | 7 (1.2%) | 6 (1.2%) | 1 (1.2%) | 1 |
| No | 599 (98.8%) | 514 (98.8%) | 85 (98.8%) | ||
| HIV *infection | Yes | 10 (1.7%) | 8 (1.5%) | 2 (2.3%) | 0.6 |
| No | 596 (98.3%) | 512 (98.5%) | 84 (97.7%) | ||
| Other comorbidities | Yes | 452 (74.6%) | 377 (72.5%) | 75 (87.2%) | 0.004 |
| No | 154 (25.4%) | 143 (27.5%) | 11 (12.8%) | ||
Values are expressed as mean (95% CI) or % as appropriate.
*HIV denotes human immunodeficiency virus