Alignment of nucleic acid sequences in regions correspond to identified HREs (15–25). Numbering refers to nucleotide position relative to the start of transcription. Arrows indicate dyad axis of symme consensus sequence is derived from nucleotides conserved with a frequency of 50% or more. Specific references for HREs can be found in Fig. 2. GRE glucocorticoid response element; MMTV, mouse mammary tumor virus; hGH, human growth hormone; MSV, murine sarcoma virus; hMTIIA, human metallothionein; TO, tyrosine oxidase; TAT, tyrosine aminotransferase; ERE, estrogen response element; xVit, Xenopus vitellogenin; cVit, chicken vitellogenin; Oval, chicken ovalbumin; rPrl, rat prolactin;TRE thyroid hormone response element; and rGH, rat growth hormone.