Leukocyte rolling (panel A), adhesion (panel B), and extravasation (panel C) were studied in all experimental groups of rats by brightfield intravital microscopy and expressed as the number of leukocytes/min, leukocytes/100-μm vessel length, and leukocytes/1000 μm2 extravascular space, respectively. AngII increases leukocyte endothelium interactions in the microcirculation, which were reduced similarly by losartan, ZLLal or PDTC treatment. Bars represent mean ± SEM, and numbers at the base of the bars represent the number of rats studied in each group.