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Mouse genotypes for MR imaging
| Cohort | Age | Strain/genotype/numbers of animals |
|---|---|---|
| Young WT | 4–6 months | C57/B6 (n = 12) |
| Young APPSwInd | 5–6 months | C57/B6, APPSwInd (n = 11) |
| Old WT | 13–17 months | C57/B6 WT (n = 1) and monogenics: tTA (n = 4) APP (n = 6) (Total n = 11) |
| Old APPSwInd | 13–17 months | C57/B6, APPSwInd (n = 6) |
Additional animals for each cohort were used for histology (see Materials and Methods).
