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. Author manuscript; available in PMC: 2018 Sep 27.
Published in final edited form as: Glob Vaccines Immunol. 2016 May 27;1(2):44–52. doi: 10.15761/GVI.1000112

Figure 5. Mtb-mediated upregulation of TLR on B cells correlates with IGRA intensity.

Figure 5

A) Percentages of TLR2+ B cells following PBMC culture with WCL from Mtb for 72 hrs correlated with the intensity of IGRA diagnostic. B) In contrast, percentages of TLR4+ B cells following PBMC culture with WCL did not correlate with the intensity of IGRA. C. TLR2+ HEK cells respond to WCL by secreting IL-8 (left side of plot), but there was a weak response from TLR4+ HEK cells to WCL (right side of plot.)