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. Author manuscript; available in PMC: 2018 Sep 27.
Published in final edited form as: Glob Vaccines Immunol. 2016 May 27;1(2):44–52. doi: 10.15761/GVI.1000112

Figure 6. B cells from non-elderly subjects respond similarly to those from elderly subjects.

Figure 6

A. B cells within PBMCs express CD69, TLR2 and CD77 as well as CD38 (B) in response to WCL following culture; *indicates a statistically significant difference in means from media alone; P<0.02. C. B cells within PBMCs express additional markers of activation, including CD86 and CD95 in response to WCL. A combination of Pam3CSK4 and E. coli LPS also induced CD86 and CD95. **indicates means of stimuli-induced activation differed from media alone; P<0.02. D) Mucosal B cells demonstrate similar responses to WCL and upregulate CD69, TLR2 and CD77. *indicates a statistically significant difference compared to media alone; P<0.02. All data shown is at the 72 hour time point and n=3 separate experiments.