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. 2018 Sep 21;11:6153–6165. doi: 10.2147/OTT.S175428

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© 2018 Cao et al. This work is published and licensed by Dove Medical Press Limited

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CPEB4 induced GC cells’ migration, invasion, and growth via ZEB1-mediated EMT.

Notes: (A) Insight into the ZEB1-dependent mechanism of CPEB4-induced GC cells’ EMT by Western blot. (B) Confirmation of the ZEB1-dependent mechanism of CPEB4-facilitating GC cells’ migration and invasion by transwell assay. Exploration of the ZEB1-dependent mechanism of CPEB4-induced GC cells growth by the CCK-8 assay. Magnification ×200. (C), EdU assay (D), and colony formation assay. Magnification ×100. (E). ^*P<0.05.

Abbreviations: CCK-8, cell-counting kit-8; CPEB4, cytoplasmic polyadenylation element-binding protein 4; EMT, epithelial–mesenchymal transition; GC, gastric cancer.