Table 3.

Het/Hom ratio and number of variants called in the 462 lymphoblastoid cell lines

Population*	Number of Individuals	Number of Heterozygous Variants Median (IQR)	Number of Homozygous Variants, Median (IQR)	Het/Hom ratio, Median (IQR)
CEU	91	24,301 (21,185–28,283)	32,199 (26,771–38,394)	0.770 (0.730–0.800)
FIN	95	26,473 (22,500–30,951)	34,623 (28,876–41,536)	0.770 (0.739–0.799)
GBR	94	26,794 (23,991–33,319)	35,563 (30,866–43,821)	0.773 (0.744–0.797)
TSI	93	25,750 (22,514–29,834)	33,005 (27,534–38,355)	0.776 (0.747–0.817)
YRI	89	34,524 (29,252–41,074)	38,646 (32,666–46,137)	0.866 (0.839–0.890)

^*Residents from Utah, USA with Northern and Western European ancestry (CEU), Finnish in Finland (FIN), British in England and Scotland (GBR), Tuscany in Italy (TSI), and Yoruba in Ibadan, Nigeria (YRI). The difference in the Het/Hom ratio among the groups was statistically significant (P<0.0001, Kruskal -Wallis test). By Dunn’s test, the difference in the Het/Hom ratio between YRI and each of the other four groups was statistically significant (P<0.05). None of the other pair-wise comparisons were statistically significant (all P>0.05).