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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Burns. 2018 Mar 27;44(7):1738–1749. doi: 10.1016/j.burns.2018.02.029

Figure 4. Significant reduction of the human CD4+T cell response to dominant-negative mutant class II transactivator (CIITA-DN) porcine aortic endothelial cells.

Figure 4

Human (h) CD4+T cells were co-cultured with pAECs for 7 days (n=6). The response of hCD4+T cells was evaluated by [3H] thymidine incorporation. As a negative control, hCD4+T cells were cultured with culture medium (spont). There was a significantly lower hCD4+T cell response to CIITA-DN pAECs compared with WT pAECs (**P<0.01). (Reproduced with permission from Hara H, et al. Immunology. 2013;140:39–46.)