Table 2.
Adverse events related to CART-HER2 therapy
| AEs | Conditioning section | Infusion section | Post-infusion section | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Any grade | Grade 3–4 | Any grade | Grade 3–4 | Any grade | Grade 3–4 | |||||||
| N | % | N | % | N | % | N | % | N | % | N | % | |
| Oral mucositis | 2 | 18.2 | ||||||||||
| Gastrointestinal hemorrhage | 1 | 9.1 | 1 | 9.1 | 1 | 9.1 | ||||||
| Skin pruritus | 1 | 9.1 | 1 | 9.1 | ||||||||
| Anemia | 3 | 27.3 | 3 | 27.3 | ||||||||
| Lymphopenia | 9 | 81.8 | 6 | 54.5 | 3 | 27.3 | ||||||
| Thrombocytopenia | 2 | 18.2 | ||||||||||
| Acute fever/Chill | 2 | 18.2 | 11 | 100 | 1 | 9.1 | ||||||
| Delayed fever/Chill | 2 | 18.2 | ||||||||||
| Fatigue | 7 | 63.6 | 4 | 36.4 | ||||||||
| Transaminase elevation | 2 | 18.2 | 1 | 9.1 | ||||||||
| Diarrhea | 1 | 9.1 | ||||||||||
| Nausea/Vomiting | 8 | 72.7 | 1 | 9.1 | ||||||||
| Myalgia/Arthralgia | 5 | 45.5 | ||||||||||