Table 2.
CMR imaging characteristics in the study population.
| Variables | Control group (n = 30) | Test group | p-Value* | |
|---|---|---|---|---|
| No PH (n = 14) | PH (n = 16) | |||
| LV EDV index, mL/m2, mean (SD) | 71.3 (12.4) | 63.6 (10.2) | 61.1 (10.6) | NS |
| LV ESV index, mL/m2, mean (SD) | 25.1 (4.4) | 27.2 (5.5) | 26.9 (3.8) | 0.01 |
| LV ejection fraction, %, mean (SD) | 64.1 (6.6) | 59.5 (2.7) | 57.5 (2.4) | <0.001 |
| LV mass index, g/m2, mean (SD) | 57.4 (17.9) | 67.9 (8.1) | 65.3 (13.0) | 0.01 |
| LA area, cm2/m2, mean (SD) | 8.2 (3.2) | 10.0 (2.2) | 10.1 (2.7) | 0.001 |
| RV EDV index, mL/m2, mean (SD) | 62.1 (12.1) | 72.1 (13.3) | 79.5 (10.1) | NS |
| RV ESV index, mL/m2, mean (SD) | 23.2 (8.8) | 30.6 (6.7) | 41.1 (6.6) | <0.001 |
| RV ejection fraction, %, mean (SD) | 63.8 (9.4) | 57.6 (3.4) | 48.1 (5.1) | <0.001 |
| RV mass index, g/m2, mean (SD) | 22.6 (5.4) | 33.4 (7.1) | 41.6 (7.2) | <0.001 |
| RA area, cm2/m2, mean (SD) | 8.6 (2.3) | 10.4 (2.5) | 11.1 (1.4) | <0.001 |
| TAPSE, mm, mean (SD) | 20.7 (3.7) | 15.4 (2.4) | 15.7 (3.1) | <0.001 |
| RV/LV mass ratio, mean (SD) | 0.42 (0.15) | 0.48 (0.07) | 0.64 (0.08) | 0.001 |
| PA: AA diameter ratio | 0.91 (0.13) | 0.97 (0.13) | 1.1 (0.14) | <0.001 |
| Maximal PA area, cm2, mean (SD) | 8.2 (1.4) | 9.4 (1.5) | 10.4 (1.9) | <0.001 |
| Minimal PA area, cm2, mean (SD) | 5.8 (1.1) | 7.1 (1.2) | 7.9 (1.3) | <0.001 |
| PA elasticity, %, median (IQR) | 41.5 (24–116) | 38.5 (12–44) | 29.5 (15–53) | 0.001 |
| PA distensibility, %/mmHg, median (IQR) | 1.26 (0.39–3.60) | 0.73 (0.25–2.39) | 0.51 (0.23–1.02) | 0.001 |
| PA compliance, mm2/mmHg, median (IQR) | 25.0 (10–50) | 10.8 (3.6–46.0) | 6.4 (3.7–11.1) | <0.001 |
| PA elastic modulus, mmHg, median (IQR) | 24 (14–63) | 64 (11–190) | 137 (82–216) | <0.001 |
| PA stiffness index beta, median (IQR) | 2.0 (1.1–3.4) | 2.7 (0.53–8.1) | 2.9 (2.1–7.4) | <0.001 |
| PA capacitance, mm3/mmHg, median (IQR) | 9.8 (4.4–19.6) | 3.1 (1.7–13.4) | 1.8 (1.4–3.0) | <0.001 |
| PWV, m/s, mean (SD) | 2.10 (0.7) | 5.58 (1.4) | 9.71 (2.2) | <0.001 |
Abbreviations: AA, ascending aorta; LA, left atrium; LV, left ventricle; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; PH, pulmonary hypertension; RA, right atrium; RV, right ventricle; RVEDV, right ventricular end-diastolic volume; RVESV, right ventricular end-systolic volume TAPSE, tricuspid annular plane systolic excursion; PA, pulmonary artery; PWV, pulse wave velocity; IQR, interquartile range; SD, standard deviation.
*Represents statistical significance between groups.