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. 2018 Sep 27;8:14446. doi: 10.1038/s41598-018-32758-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Schematic illustration of PLPEG, CNT, and a supposed structure of PLPEG-CNT. (B) Fluorescent spectrum of PLPEG-CNT dispersed in water. The black rectangular in “B” denotes the excitation and fluorescence wavelength region used in the imaging. (C) Time table of fasting, feeding, intravenous injection (i.v.) of PLPEG-CNT, and dissection (Diss.). (D) Images of fasted mice at PIT 12 minutes (a,b), 5 h (c,d), and (1D,e,f). Dorsal images (a,c,e) and ventral images (b,d,f). Image-signal-intensity ranges denoted with yellow numbers are optimized for the whole-body visualization at each time point (n = 4).