Table 2.
Effect of VCO supplemented diet on serum oxidative stress markers- SOD, CAT, and GPx (U/mg protein), GSH (mg/g protein) and MDA (nmol/mg protein) of MTX-treated rats.
| Group | SOD | CAT | GPx | GSH | MDA |
|---|---|---|---|---|---|
| Control | 0.22 ± 0.01 | 9.83 ± 0.20 | 44.3 ± 1.70 | 4.50 ± 0.16 | 1.25 ± 0.30 |
| MTX | 0.18 ± 0.01* | 7.46 ± 0.22* | 19.6 ± 2.00* | 3.36 ± 0.24* | 2.18 ± 0.20* |
| VCO (5%) + MTX | 0.22 ± 0.01# | 8.67 ± 0.19# | 32.2 ± 0.66# | 3.91 ± 0.02# | 0.93 ± 0.23# |
| VCO (15%) + MTX | 0.23 ± 0.01# | 10.2 ± 0.28# | 34.5 ± 1.28# | 4.29 ± 0.10# | 1.02 ± 0.03# |
VCO: Virgin coconut oil; MTX: Methotrexate; Values are mean + SEM (6 rats/group).
*
p < 0.01: significant when compared to control group in the same column.
#
p < 0.01: significant when compared to MTX group in the same column.