Table 1. Serial laboratory results at admission and after discharge.
Variable | Reference range | Day 0 | Day 32 | Day 35 | Day 59* | Day202# |
White-cell count (/mm3) | 4000-10000 | 9400 | 11200 | 7300 | 5400 | 5200 |
Hemoglobin (g/dl) | Men: 13-17 | 7.5 | 8.9 | 10.8 | 11.5 | 13.2 |
Woman: 12-15 | ||||||
Platelet (/mm3) | 150000-400000 | 68000 | 172000 | 189000 | 241000 | 207000 |
INR | 0.9-1.2 | 1 | 0.94 | - | - | - |
aPTT (sec) | 20-40 | 30 | 19.6 | - | - | - |
Reticulocytes (%) | 0.6-2.1 | 4.38 | - | - | - | - |
Hepatoglobin (mg/dL) | 30-200 | < 10 | 10.3 | 81.3 | 112.9 | 81.2 |
LDH (U/L) | 50-150 | 922 | 200 | 249 | 241 | 216 |
GOT (U/L) | 43250 | 49 | - | - | - | - |
GPT (U/L) | 5-35 | 25 | - | - | - | - |
Total bilirubin (mg/dL) | 0.3-2.0 | 2.4 | - | - | - | - |
Direct bilirubin (mg/dL) | 0-0.3 | 0.3 | - | - | - | - |
Alk-P (U/L) | 50-100 | 84 | - | - | - | - |
Total protein (mg/dL) | 6.0-8.0 | - | - | - | - | |
Albumin (g/dL) | 3.5-5.5 | 3.5 | - | - | 4.3 | 4.3 |
Urea nitrogen (mg/dl) | 43333 | 85 | 33 | 63 | 52 | 56 |
Creatinine (mg/dl) | 0.8-1.3 | 8.9 | 5.73 | 6.98 | 4.63 | 2.69 |
eGFR (mL/min/1.73 m2) | > 90 | 4.86 | 8.0 | 6.0 | 10 | 18 |
Sodium (mmol/L) | 136-145 | 126 | 132 | 136 | 138 | 136 |
Potassium (mmol/L) | 3.5-5.0 | 3.5 | 3.6 | 3.8 | 3.5 | 4 |
Calcium (mg/dl) | 9.0-10.5 | - | 9.8 | 9.5 | 9.8 | 9.7 |
Phosphorus (mg/dl) | 3.0-4.5 | - | 3.2 | 3.4 | 3.6 | 4.2 |
bicarbonate (mmol/L) | 24-26 | - | 23 | 19 | 26 | 23 |
NT-proBNP (pg/ml) | < 125 | 14500 | - | - | - | - |
C-reactive protein (mg/dL) | < 0.5 | 0.3 | - | - | - | - |
Troponin I (ng/ml) | < 0.3 | 0.35 | - | - | - | - |
* After 4 doses of Eculizumab (post induction phase) injection. # After 15 doses of Eculizumab injection.
Alk-P, alkaline phosphatase; aPTT, activated partial thromboplastin time; eGFR, estimated glomerular filtration rate; GOT, glutamate oxaloacetate transaminase; GPT, alanine aminotransferase; INR, international normalized ratio; LDH, lactate dehydrogenase; NT-proBNP, N-terminal pro-brain natriuretic peptide.