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Figure 3.

Figure 3

Comparison of frequencies changes of Treg and Th17 cell and expression changes of Foxp3 and RORC mRNA induced by rHMGB1 in atherosclerosis (AS) and normal coronary arteries (NCA) group (AS, n = 5; NCA, n = 5). (A) and (B) Comparison of Treg and Th17 cell frequencies with or without 100 ng/mL rHMGB1 stimulation for 24 h in each group; (C) and (D) Average change of Treg and Th17 cell numbers in two groups after rHMGB1 stimulation; (E) and (F) Comparison of Foxp3 and RORC mRNA levels with or without 100 ng/mL rHMGB1 stimulation for 24 h in each group; (G) and (H) Average change of Foxp3 and RORC mRNA levels in two groups after rHMGB1 stimulation. (* p < 0.05, ** p < 0.01)