Table 2. Univariate and multivariate Cox regression analysis of clinicopathological factors and OS.
| Characteristics | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | ||
| Age | 1.030 | 0.991–1.070 | 0.135 | ||||
| Sex | 0.605 | 0.227–1.613 | 0.315 | ||||
| Height | 1.013 | 0.972–1.056 | 0.542 | ||||
| Weight | 0.981 | 0.955–1.007 | 0.144 | ||||
| BMI | 0.896 | 0.809–0.993 | 0.037 | 0.894 | 0.791–1.011 | 0.074 | |
| Sarcopenia | 3.885 | 1.754–8.607 | 0.001 | 10.915 | 3.195–37.288 | 0.001 | |
| ASA-PS group ≥2 | 0.680 | 0.310–1.494 | 0.337 | ||||
| CCI ≥3 | 1.416 | 0.625–3.209 | 0.404 | ||||
| Neoadjuvant therapy | 1.255 | 0.569–2.768 | 0.573 | ||||
| Type of surgery | |||||||
| Total gastrectomy | 1 | ||||||
| Distal gastrectomy | 1.330 | 0.467–3.791 | 0.594 | ||||
| Proximal gastrectomy | 1.596 | 0.609–4.182 | 0.341 | ||||
| Tumor site | |||||||
| Cardia | 1 | ||||||
| Fundus | 1.225 | 0.259–5.786 | 0.798 | ||||
| Body | 1.370 | 0.514–3.687 | 0.525 | ||||
| Antrum | 0.683 | 0.223–2.093 | 0.505 | ||||
| Pylorus | 0.737 | 0.156–3.481 | 0.700 | ||||
| Stage | |||||||
| 0–1B | 1 | 1 | |||||
| 2A–2B | 10.749 | 2.320–49.804 | 0.002 | 50.177 | 7.682–327.752 | <0.001 | |
| 3A–3C | 19.610 | 4.366–88.079 | <0.001 | 56.377 | 9.175–346.407 | <0.001 | |
| Number of LNs resected | 1.012 | 0.979–1.047 | 0.485 | ||||
Statistically significant values in bold.
OS = overall survival; HR = hazard ratio; CI = confidence interval; BMI = body mass index; ASA-PS = American Society of Anesthesiologists physical status; CCI = Charlson comorbidity index; Stage = overall TNM staging as per American Joint Committee on Cancer 7th edition.