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. 2018 Sep 21;6:386. doi: 10.3389/fchem.2018.00386

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Copyright © 2018 Ma, Liu, Xi, Hou, Li, Niu, Liu, Bi, Wang, Wang, Wang, Xie and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Scheme 1 — Synthetic route of target compounds 1c-6c and 5a. Conditions and reagents: (a) H₂O₂ (30% w/v)/H₂O; (b) Succinic anhydride, DMSO; (c) HATU, DIPEA, and DMF, r.t.