Table 3.
Eliciting dose (ED) thresholds by food.
| Challenge Food | N | Number of subjects (% of total) | Eliciting dose (mg) median (range) | Eliciting dose curves (ED) (mg) (95% CI) | ||
|---|---|---|---|---|---|---|
| ED5 | ED10 | ED50 | ||||
| Almond✤ | 30 | 29 (7) | 25.0 (5–500) | 0.86 (0, 1.92) | 1.73 (0, 3.60) | 20.77 (5.76, 35.78) |
| Cashew | 151 | 150 (35) | 25.0 (0.1–500) | 0.07 (0, 0.13) | 0.25 (0.05, 0.46) | 8.78 (5.40, 12.16) |
| Egg | 63 | 60 (14) | 8.1 (0.1–500) | 0.04 (0, 0.12) | 0.18 (0, 0.42) | 7.07 (2.61, 11.54) |
| Hazelnut | 68 | 65 (15) | 25.0 (1.6–500) | 0.07 (0, 0.17) | 0.29 (0, 0.68) | 14.38 (5.36, 23.39) |
| Milk | 67 | 66 (15) | 32.7 (1.7–500) | 0.21 (0, 0.49) | 0.74 (0, 1.55) | 20.41 (9.73, 31.09) |
| Peanut | 347 | 330 (77) | 75.0 (0.1–500) | 0.49 (0.24, 0.73) | 1.52 (0.89, 2.15) | 29.90 (23.81, 35.98) |
| Pecan✤ | 88 | 88 (21) | 25.0 (1.7–500) | 0.38 (0.04, 0.71) | 0.79 (0.19, 1.39) | 10.68 (5.71, 15.64) |
| Pistachio | 60 | 59 (14) | 5.0 (5–275) | 0 (0, 0.1) | 0.01 (0, 0.04) | 1.71 (0, 3.61) |
| Sesame | 30 | 30 (7) | 25.0 (5–500) | 0.26 (0, 0.75) | 0.88 (0, 2.24) | 21.19 (5.28, 37.10) |
| Walnut | 121 | 120 (28) | 25.0 (1.7–500) | 0.15 (0, 0.31) | 0.56 (0.07, 1.05) | 18.01 (10.54, 25.47) |
| Wheat | 13 | 13 (3) | 32.7 (5–500) | 0.03 (0, 0.17) | 0.16 (0, 0.75) | 12.64 (0, 33.20) |
All models fit to Weibull distribution unless otherwise noted by✤ (Log-normal).