Table 5.
Univariate associations of severity.
| Characteristic | Not Severe | Severe | Hazard ratio (95% CI) | Challenges included |
|---|---|---|---|---|
| Female | 40% | 39% | 0.96 (0.6, 1.53) | 905 |
| Hispanic | 98% | 99% | 1.11 (0.14, 8.74) | 887 |
| Race (ref = Caucasian) | 895 | |||
| Black | 1% | 1% | 0.93 (0.11, 7.88) | |
| Asian | 29% | 37% | 1.56* (0.95, 2.59) | |
| Multiracial | 11% | 5% | 0.62 (0.23, 1.69) | |
| ATOPIC HISTORY | ||||
| Asthma | 60% | 76% | 2.37** (1.36, 4.13) | 825 |
| Allergic rhinitis | 77% | 82% | 1.1 (0.59, 2.04) | 812 |
| Atopic dermatitis | 77% | 75% | 1.05 (0.59, 1.86) | 813 |
| Age | 8 | 8 | 0.99 (0.96, 1.03) | 905 |
| FEV1 | 99 | 99 | 1 (0.98, 1.03) | 494 |
| FEV1/FVC | 0.85 | 0.86 | 4.23 (0.04, 457.57) | 492 |
| Mono-Allergic | 2% | 2% | 0.51 (0.09, 3.02) | 905 |
| Number of diagnosed food allergies | 6 | 5 | 1 (0.93, 1.09) | 905 |
| sIgE (log-scale) | 17 | 43 | 1.49*** (1.19, 1.85) | 575 |
| tIgE (log-scale) | 439 | 583 | 1.2 (0.81, 1.78) | 385 |
| sIgEr (log-scale) | 0.04 | 0.06 | 1.84*** (1.3, 2.59) | 385 |
| SPT | 12 | 13.5 | 1.04* (1, 1.08) | 600 |
Each column corresponds to a single frailty model. SPT, skin prick test; sIgE, allergen-specific Immunoglobulin E; sIgEr, ratio of sIgE to total IgE (tIgE). Values in the “Not Severe” and “Severe” columns are the percentages, means, and medians for each characteristic on the raw scale. Median values are presented for age and each biomarker.
*
p < 0.10;
**
p < 0.05;
***
p < 0.01.