Table 2.
Within-group differences between high and low T-tau/Aβ42 or P-tau/Aβ42 in NC or MCI groups.
| T-tau/Aβ42 |
P-tau/Aβ42 |
|||||
|---|---|---|---|---|---|---|
| Parameter (group) | High (14) | Low (27) | p-value | High (11) | Low (30) | p-value |
| FDG-PET (NC) | 6.40 ± 0.44 | 6.79 ± 0.48 | 0.015 | |||
| Visual occipital (NC) | 1.10 ± 0.47 | 1.49 ± 0.41 | 0.010 | |||
| Visual lateral (NC) | 1.63 ± 0.78 | 2.45 ± 1.08 | 0.017 | |||
| DMN (NC) | 5.62 ± 1.35 | 6.45 ± 1.15 | 0.044 | |||
| Left frontoparietal (NC) | 3.12 ± 1.04 | 2.44 ± 0.88 | 0.044 | |||
| Parameter (group) | High (23) | Low (41) | p-value | High (23) | Low (41) | p-value |
| FDG-PET (MCI) | 6.20 ± 0.57 | 6.53 ± 0.50 | 0.020 | 6.20 ± 0.57 | 6.53 ± 0.50 | 0.020 |
| Hippo/WholeBrain % (MCI) | 0.67 ± 0.08 | 0.73 ± 0.08 | 0.006 | |||
| Hippo/ICV % (MCI) | 0.45 ± 0.07 | 0.50 ± 0.07 | 0.011 | |||
| Ento/WholeBrain (%) (MCI) | 0.32 ± 0.08 | 0.36 ± 0.05 | 0.013 | |||
| MidT/WholeBrain (%) (MCI) | 1.86 ± 0.14 | 1.95 ± 0.15 | 0.033 | |||
| MidT/ICV (%) (MCI) | 1.27 ± 0.13 | 1.34 ± 0.12 | 0.042 | |||
The numbers in parentheses after High or Low are subject number.
Abbreviations: NC, normal; MCI, mild cognitive impairment; FDG-PET, fluorodeoxyglucose uptake on PET; DMN, default mode network; Hippo, hippocampus; WholeBrain, whole-brain volume; ICV, intracranial volume.