Figure 2.
Effect of pretreatment with simvastatin on the number of CFU in peritoneum. Animals received water (CLP group) or simvastatin (Simvastatin group) orally for 30 days when CLP was induced. Each group consisted of 5 animals. After 12 h of CLP, aliquots of the peritoneal lavage were diluted and plated on Mueller-Hinton agar and incubated at 37°C for 18 h for counting of CFU. The data are represents as mean ± S.D. of CFU × 104. The Naïve group received no procedures and the Sham group was submitted to all the procedures with exception of cecum perforation. *p < 0.05 compared to CLP group. #p < 0.05 when compared to the Sham group.