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. 2018 Aug 24;8(9):e01086. doi: 10.1002/brb3.1086

Table 2.

Treatment‐induced sparing. Anatomic location of areas of reduced gray matter loss in estriol + glatiramer acetate (GA) cohort compared to placebo + GA cohort after 12 months of treatment

Anatomic structure MNI coordinates Cluster size (voxels) Cluster size (ml) Z score
X Y Z
Left frontal cortex −22 14 48 3,382 11.4 4.68
Medial parietal cortex 4 −7 64 2,203 7.4 4.61
Left parietal cortex −44 −46 46 1,817 6.1 4.12
Medial frontal cortex −2 38 36 1,393 4.7 4.43
Left parietal cortex −60 −22 31 731 2.5 4.23
Right temporal cortex 56 0 9 642 2.2 4.29
Medial parietal cortex 4 −51 12 490 1.7 4.16
Medial occipital cortex 3 −64 −3 297 1.0 4.19

MNI, coordinates (x, y, z) according to Montreal Neurological Institute space.