Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic diagram outlining the functional roles of SPOP. (A). Diagram of the normal functions of SPOP and how these are interrupted by mutations and/or loss of expression in Prostate, Endometrial, Breast, Brain, Colorectal, Gastric, Liver, Lung, Ovary, and Thyroid Cancers. (B). Diagram of how overexpression and localization to the cytoplasm alters SPOP function in Kidney Cancer.
