Table 2.

List of SPOP alterations

Description of SPOP Alterations in Different Cancer Subtypes
Organ	Type(s) of Alteration(s)
Prostate	Missense Mutations, Loss of Expression
Endometrium	Missense Mutations, Loss of Expression
Breast	Loss of Expression
Brain	Loss of Expression
Colorectal	Loss of Expression
Gastric	Loss of Expression
Kidney	Overexpression, Cytoplasmic Localization
Liver	Missense Mutations
Ovary	Amplification, Deletion
Thyroid	Missense Mutations
Lung	Loss of Expression