Table 2.
Annual survival rates and their comparisons of OS and PFS in different subgroups of patients
| OS% (P-value) | PFS% (P-value) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 year | 2 years | 3 years | 4 years | 5 years | SD | 1 year | 2 years | 3 years | 4 years | 5 years | SD | |
| Total patients | ||||||||||||
| I | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 |
| II | 99.2(0.125) | 98.4(0.250) | 96.9(1.000) | 96.1(1.000) | 96.1 | 1.3 | 99.2(0.004) | 96.1(0.125) | 94.6(0.250) | 93.0(1.000) | 92.2 | 2.5 |
| III | 99.3 | 97.9 | 96.0 | 94.3(0.004) | 92.2 | 2.5 | 97.2 | 92.9 | 89.8 | 87.0(0.008) | 85.1 | 4.3 |
| IVA | 96.9 | 91.9 | 87.3 | 79.2(0.004) | 75.4 | 7.9 | 91.2 | 82.3 | 75.4 | 71.5(0.031) | 69.2 | 8.0 |
| EBV<103 | ||||||||||||
| I | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 |
| II | 100.0(0.375) | 99.0(0.500) | 98.1(1.000) | 97.1(1.000) | 97.1 | 1.1 | 100.0(0.070) | 98.1(0.250) | 96.1(0.500) | 95.1(1.000) | 94.2 | 2.1 |
| III | 99.5 | 97.9(0.016) | 96.4(0.063) | 95.8(0.125) | 93.7 | 2.0 | 97.9 | 94.8 | 91.7(0.031) | 90.1(0.25) | 88.5 | 3.4 |
| IVA | 100.0 | 97.5 | 94.9(<0.001) | 87.3(0.063) | 79.7 | 7.4 | 97.5 | 88.6 | 81.0(0.008) | 74.7(0.25) | 70.9 | 9.6 |
| 103≤EBV<105 | ||||||||||||
| I | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 |
| II | 95.7(1.000) | 95.7(1.000) | 91.3(1.000) | 91.3(1.000) | 91.3 | 2.2 | 95.7(0.500) | 87.0(1.000) | 87.0(1.000) | 87.0(1.000) | 87.0 | 3.5 |
| III | 99.0 | 97.4 | 95.9(<0.001) | 93.4(0.063) | 90.8 | 2.9 | 95.9 | 92.3 | 89.3(<0.001) | 85.7(0.125) | 83.7 | 4.4 |
| IVA | 95.6 | 90.5 | 84.7(<0.001) | 75.9(0.250) | 73.7 | 8.4 | 89.1 | 80.3(<0.001) | 73.7(0.125) | 71.5(1.000) | 70.8 | 6.9 |
| EBV≥105 | ||||||||||||
| I | ||||||||||||
| II | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 66.7(1.000) | 66.7 | 16.3 |
| III | 100.0(0.375) | 100.0(0.375) | 94.3(1.000) | 91.4(1.000) | 91.4 | 3.9 | 100.0(0.012) | 85.7(0.125) | 82.9(0.250) | 77.1(1.000) | 74.3 | 9.0 |
| IVA | 95.5(0.002) | 86.4(0.063) | 81.8(0.125) | 75.0(1.000) | 72.7 | 8.2 | 86.4 | 77.3(0.031) | 70.5(0.250) | 65.9(0.500) | 61.4 | 8.8 |
EBV: Epstein-Barr viral; OS: overall survival; PFS: progression-free survival; SD: standard deviation is calculated from five annual survival rates; P-value: Comparisons between survival rates until the difference is statistically significant