Table 3.
Annual survival rates and their comparisons of LRFS and DMFS in different subgroups of patients
| LRFS% (P-value) | DMFS% (P-value) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 year | 2 years | 3 years | 4 years | 5 years | SD | 1 year | 2 years | 3 years | 4 years | 5 years | SD | |
| Total patients | ||||||||||||
| I | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 |
| II | 100.0(0.070) | 97.6(0.500) | 96.9(0.500) | 96.1(1.000) | 95.3 | 1.6 | 99.2(0.250) | 98.4(0.250) | 98.4(0.500) | 96.9(1.000) | 96.1 | 1.1 |
| III | 99.5 | 98.1 | 96.1(0.002) | 94.7(0.125) | 93.7 | 2.1 | 97.9 | 95.3 | 93.6(0.002) | 92.2(0.125) | 91.2 | 2.4 |
| IVA | 98.4 | 95.2(0.004) | 92.3(0.250) | 91.4(1.000) | 90.9 | 2.8 | 93.0 | 86.0(<0.001) | 82.5(0.125) | 80.8(1.000) | 80.4 | 4.7 |
| EBV<103 | ||||||||||||
| I | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 |
| II | 100.0(0.375) | 99.0(1.000) | 98.0(1.000) | 98.0(1.000) | 97.0 | 1.0 | 100.0(0.219) | 99.0(0.250) | 99.0(0.250) | 97.1(1.000) | 96.1 | 1.4 |
| III | 99.5 | 99.5(0.004) | 97.3(0.063) | 95.7(0.500) | 94.6 | 2.0 | 98.4(0.004) | 95.8(0.250) | 94.8(0.500) | 94.3(1.000) | 93.7 | 1.7 |
| IVA | 100.0(0.125) | 97.5(0.250) | 94.9(1.000) | 93.5(1.000) | 93.5 | 2.5 | 97.5 | 89.9(0.016) | 84.8(0.250) | 80.9(1.000) | 80.9 | 6.3 |
| 103≤EBV<105 | ||||||||||||
| I | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 |
| II | 100.0(0.625) | 90.9(1.000) | 90.9(1.000) | 90.9(1.000) | 90.9 | 3.6 | 95.7(1.000) | 95.7(1.000) | 95.7(1.000) | 95.7(1.000) | 95.7 | 0.0 |
| III | 99.5 | 98.4(0.008) | 96.3(0.125) | 95.3(0.500) | 94.2 | 2.0 | 96.9 | 94.4 | 92.3(0.031) | 90.3(0.500) | 89.2 | 2.8 |
| IVA | 97.0(0.008) | 94.7(0.125) | 91.5(1.000) | 91.5(1.000) | 90.6 | 2.4 | 92.6(<0.001) | 85.2(0.500) | 82.9(1.000) | 82.9(1.000) | 82.9 | 3.8 |
| EBV≥105 | ||||||||||||
| I | ||||||||||||
| II | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 66.7(1.000) | 66.7 | 16.3 | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0(1.000) | 100.0 | 0.0 |
| III | 100.0(0.125) | 88.6(1.000) | 88.6(1.000) | 85.6(1.000) | 85.6 | 5.3 | 100.0(0.219) | 97.1(0.250) | 94.2(0.500) | 91.3(1.000) | 88.4 | 4.1 |
| IVA | 100.0(0.125) | 92.6(0.500) | 90.0(1.000) | 87.3(1.000) | 87.3 | 4.7 | 86.4(0.310) | 81.8(0.250) | 77.2(1.000) | 74.8(1.000) | 72.3 | 5.0 |
EBV: Epstein-Barr viral; LRFS: Loco-regional recurrence-free survival; DMFS: Distant metastasis-free survival; SD: standard deviation is calculated from five annual survival rates; P-value: Comparisons between survival rates until the difference is statistically significant