Table 1.
Levels of plasma antioxidants, lipids, and prosaposin in sepsis patients at the time of hospitalization as compared to age-matched healthy controls (average ± SD)
| Sepsis | Normal control | p | |
|---|---|---|---|
| n | 18 | 62 | |
| Male/Female | 8/10 | 25/37 | |
| Age (years) | 74.8 ± 15.1 | 75.6 ± 8.1 | |
| VC (µM) | 15.1 ± 25.7 | 46.2 ± 18.4 | <0.001 |
| UA (µM) | 407 ± 143 | 327 ± 63 | <0.05 |
| BR (µM) | 5.9 ± 5.4 | 6.0 ± 4.6 | |
| VE (µM) | 28.1 ± 10.0 | 33.3 ± 9.8 | |
| TQ10 (µM) | 758 ± 368 | 880 ± 313 | |
| %CoQ10 | 41.4 ± 36.8 | 12.7 ± 9.5 | <0.05 |
| FFA (µM) | 667 ± 359 | 501 ± 233 | |
| %PUFA | 16.0 ± 3.5 | 23.4 ± 4.9 | <0.001 |
| %16:1 | 5.3 ± 2.0 | 4.2 ± 1.8 | |
| %18:1 | 40.9 ± 2.7 | 33.6 ± 6.6 | <0.001 |
| FC (mM) | 1.05 ± 0.59 | 1.31 ± 0.28 | <0.001 |
| CE (mM) | 1.87 ± 0.87 | 3.03 ± 0.61 | <0.001 |
| TC (mM) | 2.96 ± 1.26 | 4.33 ± 0.83 | <0.001 |
| FC/CE | 0.74 ± 0.67 | 0.44 ± 0.08 | |
| 103 VE/TC | 10.3 ± 3.7 | 8.6 ± 2.4 | <0.05 |
| 106 TQ10/TC | 303 ± 237 | 205 ± 69 | |
| Psap (nM) | 25.3 ± 10.2 | 34.8 ± 7.4 | <0.01 |
P values were determined using Mann-Whitney’s U test. VC, ascorbic acid; UA, uric acid; BR, unconjugated bilirubin; VE, vitamin E; TQ10, total coenzyme Q10; %CoQ10, ratio of oxidized form of coenzyme Q10 to TQ10; FFA, free fatty acids; %PUFA, ratio of polyunsaturated fatty acids to total FFA; %16:1, ratio of palmitoleic acid to total FFA; %18:1, ratio of oleic acid to total FFA; FC, free cholesterol; CE, cholesterol esters; TC, total cholesterol; Psap, prosaposin.