Table 3.
Detection of Yersinia species in samples from the three cohorts.
| Cohort 1 (O'Brien et al., 2014) | Cohort 2 (unpublished) | Cohort 3 (Fumery et al., 2017) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Disease status | CD (n = 34) | controls (n = 31) | CD (n = 17) | controls (n = 45) | CD (n = 211) | ||||||
| Sample's area (n) | NIA (28) | IA (30) | LN (28) | NIA (25) | IA (29) | LN (25) | PP (17) | IM (16) | PP (26) | IM (35) | IA (211) |
| gyrB for YE | 0 | 3 | 1 | 3 | 2 | 2 | 0 | 0 | 2 | 0 | 9 |
| ail for YE | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
| inv for YP | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 2 |
| gyrB for YB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| gyrB for YM | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| gyrB for YA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| gyrB for YI | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
| Positive samples | 2 (7%) | 4 (13%) | 1 (4%) | 4* (16%) | 2 (7%) | 3 (12%) | 1 (6%) | 0 (0%) | 2 (7%) | 0 (0%) | 17 (8%) |
CD, Crohn's Disease; NIA, Non-inflammatory area; IA, inflammatory area; LN, lymph node; PP, Peyer's patch; IM, ileal mucosa; YE, Y. enterocolitica; YP, Y. pseudotuberculosis; YB, Y.bercovieri; YM, Y. molaretii; YA, Y. aldovae; YI, Y. intermedia.
*
one patient was positive for 3 Yersinia species.