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. 2018 Sep 9;8(17):4649–4663. doi: 10.7150/thno.26789

Figure 1.

Figure 1

VASP is frequently overexpressed in HCC tissues and correlates with HCC progression and survival. (A) Left: Western blot analysis of VASP levels in paired human HCC and matched adjacent non-tumorous tissues. Right: The chart shows VASP protein expression levels in HCC specimens versus paired adjacent normal liver tissues. NT: non-tumor; T: tumor. (B) qRT-PCR for VASP was performed in 126 pairs of HCC and matched adjacent NT liver tissues. *, P<0.05 by t-test. (C) Western blot analysis of VASP levels in paired human HCC and matched adjacent NT, portal vein tumor thrombus (PVTT). (D) qRT-PCR for VASP was performed in paired HCC and matched adjacent NT, PVTT. (E) Representative images of IHC staining of VASP in differentiated HCC, NT, and PVTT. Comparison of VASP expression in HCC. 95% CI = 1.892-7.853. (F) Expression of VASP protein in normal hepatic cells (LO2 and HL-7702) and a panel of HCC cells was assessed by Western blotting. (G) Disease-free and (H) overall survival rates of 126 patients with HCC were compared between the low-VASP and high-VASP groups.