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. 2018 Sep 18;26(3):125–134. doi: 10.4250/jcvi.2018.26.e20

Table 3. Longitudinal studies that examined the association between BAC and cardiovascular disease.

Author, year Nation Population n Mean age (years) BAC prevalence Follow-up (years) Outcome HR 95% CI
Kemmeren,199834) Netherlands General 12,239 57.5 9.1% 16.8 All-cause mortality 1.29 1.06–1.58
Cardiovascular mortality 1.29 1.01–1.66
CHD mortality 1.44 1.02–2.05
Cerebrovascular mortality 0.88 0.49–1.61
Other cardiovascular mortality 1.38 0.89–2.16
Iribarren, 200435) United States General 12,761 56 3.0% 24.8 CHD 1.32 1.08–1.60
Ischemic stroke 1.41 1.11–1.78
Heart failure 1.52 1.18–1.98
Schnatz, 201136) United States General 1,454 56.3 16.3% 5 CHD 3.54 (OR) 2.28–5.50
Abou-Hassan, 201537) United States End stage renal disease 202 58.3 58.4% 4.1 Coronary artery disease 1.06 (OR) 0.48–2.38
PAD 4.56 (OR) 1.20–17.3
Hendriks, 201538) Netherlands General 1,540 57 8.6% 13.2 CHD 1.44 1.02–2.01
Stroke 1.39 0.92–2.08
PAD 1.37 0.74–2.52
Composite of CHD, stroke, PAD 1.39 1.00–1.93

BAC: breast arterial calcification, CHD: coronary heart disease, CI: confidence interval, HR: hazard ratio, n: number of patients, OR: odds ratio, PAD: peripheral arterial disease.