Table 3. Longitudinal studies that examined the association between BAC and cardiovascular disease.
Author, year | Nation | Population | n | Mean age (years) | BAC prevalence | Follow-up (years) | Outcome | HR | 95% CI |
---|---|---|---|---|---|---|---|---|---|
Kemmeren,199834) | Netherlands | General | 12,239 | 57.5 | 9.1% | 16.8 | All-cause mortality | 1.29 | 1.06–1.58 |
Cardiovascular mortality | 1.29 | 1.01–1.66 | |||||||
CHD mortality | 1.44 | 1.02–2.05 | |||||||
Cerebrovascular mortality | 0.88 | 0.49–1.61 | |||||||
Other cardiovascular mortality | 1.38 | 0.89–2.16 | |||||||
Iribarren, 200435) | United States | General | 12,761 | 56 | 3.0% | 24.8 | CHD | 1.32 | 1.08–1.60 |
Ischemic stroke | 1.41 | 1.11–1.78 | |||||||
Heart failure | 1.52 | 1.18–1.98 | |||||||
Schnatz, 201136) | United States | General | 1,454 | 56.3 | 16.3% | 5 | CHD | 3.54 (OR) | 2.28–5.50 |
Abou-Hassan, 201537) | United States | End stage renal disease | 202 | 58.3 | 58.4% | 4.1 | Coronary artery disease | 1.06 (OR) | 0.48–2.38 |
PAD | 4.56 (OR) | 1.20–17.3 | |||||||
Hendriks, 201538) | Netherlands | General | 1,540 | 57 | 8.6% | 13.2 | CHD | 1.44 | 1.02–2.01 |
Stroke | 1.39 | 0.92–2.08 | |||||||
PAD | 1.37 | 0.74–2.52 | |||||||
Composite of CHD, stroke, PAD | 1.39 | 1.00–1.93 |
BAC: breast arterial calcification, CHD: coronary heart disease, CI: confidence interval, HR: hazard ratio, n: number of patients, OR: odds ratio, PAD: peripheral arterial disease.