Table 2A.
Factual Knowledge scores distribution for FMR1 gene mutations reveals “Don't Know” as the most common answer in a cohort of PCPs and medical students in Serbia.
| Cohort | PCPs | Medical students | |
|---|---|---|---|
| STATEMENT/ANSWERS | |||
| N (%) | N (%) | P values | |
| 1. FXS is caused by the FMR1 gene FM. | |||
| Yes | 92 (32) | 113 (46.1) | |
| No | 12 (4.2) | 8 (3.3) | P = 0.005 |
| Don't know | 180 (63.4) | 124 (50.6) | |
| 2. FXS is the most common cause of inherited ID. | |||
| Yes | 80 (28.2) | 91 (37.1) | |
| No | 21 (7.4) | 68 (27.8) | P < 0.001* |
| Don't know | 183 (64.4) | 86 (35.1) | |
| 3. FXS is the most common known single gene cause of autism. | |||
| Yes | 71 (25.0) | 101 (41.2) | |
| No | 15 (5.3) | 26 (10.6) | P < 0.001* |
| Don't know | 198 (69.7) | 118 (48.2) | |
| 4. FMR1 gene PM can cause symptoms like those of Parkinson's disease. | |||
| Yes | 65 (22.9) | 74 (30.2) | |
| No | 12 (4.2) | 12 (4.9) | P = 0.134 |
| Don't know | 207 (72.9) | 159 (64.9) | |
| 5. FMR1 gene PM can cause primary ovarian insufficiency. | |||
| Yes | 55 (19.4) | 70 (28.6) | |
| No | 16 (5.6) | 17 (6.9) | P = 0.028 |
| Don't know | 213 (75.0) | 158 (64.5) | |
PCPs, primary care physicians; FXS, fragile X syndrome; FMR1, gene-Fragile X Mental Retardation 1 gene; FM, full mutations; ID, intellectual disability; PM, premutations.
N, number of the study participants; P values, probability of the data arising by chance;
*
statistically significant data.
Correct answer is ”Yes.“