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Microdialysis in the medial Prefrontal Cortex (mPFC). At t = 0 min, rats received Saline or LPS. Graph represents percentage from baseline (%) of 5-HT and 5-HIAA from each time point (min). Animals (n) per group were as follows: n = 7 for Saline-SERT+/+ rats (a,d) and n = 7 for LPS-SERT+/+ rats (a,d); n = 7 for Saline-SERT+/− rats (b,e) and n = 8 for LPS-SERT+/− rats (b,e); n = 8 for Saline-SERT−/− rats (c,f) and n = 7 for LPS-SERT−/− rats (c,f). Significance: * p < 0.05.
