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. 2018 Aug 20;10(3):133. doi: 10.3390/pharmaceutics10030133
Ae0–24h the percentage of the dose excreted in the urine during 24 h
AUC area under the plasma concentration–time curve
CL time-averaged total body clearance
CLNR time-averaged nonrenal clearance
CLR time-averaged renal clearance
Cmax maximum plasma concentration
F the extent of absolute oral bioavailability
fu unbound fraction
GI24 h the percentage of the dose recovered from the gastrointestinal tract at 24 h (including their contents and feces during 24 h)
IMP imperatorin
IS internal standard
LC-MS/MS liquid chromatographic–tandem mass spectrometry
LLOQ lower limit of quantification
MRT mean residence time
PA paeonol
PKs pharmacokinetics
SD standard deviation
SSa saikosaponin a
Tmax time to reach Cmax
Vss apparent volume of distribution at steady state