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. 2018 Jul 19;11(3):71. doi: 10.3390/ph11030071

Figure 1.

Figure 1

Live cell imaging with bioengineered aptamer tags. Fluorogenic RNA aptamers such as Mango, Corn, Broccoli, and SRB-2 Rainbow are inserted after a gene of interest, bind to their target fluorophores, and turn on fluorescence in the presence of their target fluorophores. The fluorogenic RNA aptamer tags can be used for tracking and for investigating the dynamics of a gene of interest in live cells.