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. 2018 Aug 14;4(9):1155–1165. doi: 10.1021/acscentsci.8b00332

Table 1. Rate-Limiting Steps (Membrane Entry, Flip–Flop, or Membrane Exit) for Membrane Permeation Depending on the Steroid Structure and the Type of Membrane.

  cell planar membrane LUV (radius 0.2 μm)
long-tailed exit exit exit
0–1 OH groups entry entry exit
2–3 OH groups flip–flop flip–flop flip–flop