Figure 4. . PAK1 and CED-10 is involved in the immune response to Candida albicans.
(A) pak-1 is involved in conferring the efficacy of CAPE against Candida albicans. pak-1-mutant nematodes do not respond to treatment with CAPE and the survival of CAPE-treated nematodes is not significantly different than nematodes treated with solvent alone. (B) ced-10 is involved in conferring the efficacy of CAPE against C. albicans. Nematodes suppressed by RNAi for ced-10 do not respond to treatment with CAPE and the survival of CAPE-treated nematodes is not significantly different than nematodes treated with solvent alone.
CAPE: Caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester.