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. 2018 Aug 16;13(10):1141–1156. doi: 10.2217/fmb-2018-0033

Figure 4. . Carboxin attenuates the virulence and filamentous growth of the wild-type Candida albicans.

Figure 4. 

(A) Carboxin decreases the virulence of C. albicans and dose-dependently improves the survival of worms in the Caenorhabditis elegans candidiasis model. 1.5 mM carboxin protects the C. elegans completely. (B) 1.5 mM carboxin completely inhibits the filamentation of C. albicans in vivo in the C. elegans candidiasis model. (C) Carboxin dose-dependently inhibits the filamentous growth of C. albicans in vitro. (D) Carboxin at 1.5 mM completely abolishes the growth of wild-type C. albicans on nonfermentable carbon sources.

YPD: Contains fermentable glucose as carbon source; YPE: Contains nonfermentable ethanol as carbon source; YPS: With fermentable sucrose as carbon source.