(A & B) Malonate does not attenuate the virulence and filamentation of wild-type C. albicans in the Caenorhabditis elegans candidiasis model. (C) Malonate does not affect the filamentous growth of wild-type C. albicans in vitro. (D) Malonate does not affect the growth of wild-type C. albicans on YPD, YPG and YPE agar plates. (E & F) The deletion of FUM12 does not attenuate the virulence and filamentation of C. albicans in the C. elegans candidiasis model. (G) The deletion of FUM12 does not affect the filamentous growth of C. albicans in vitro.
YPD: Contains fermentable glucose as carbon source; YPE: Contains nonfermentable ethanol as carbon source; YPG: Contains nonfermentable glycerol as carbon source; YPS: With fermentable sucrose as carbon source.