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. 2018 Jul 21;10(3):101. doi: 10.3390/pharmaceutics10030101

Figure 6.

Figure 6

(a) Comparison of the ranges of ΔECoul and diffusion coefficients for FLA vs. PAC. The polymers are in the order of increasing ΔECoul: PVP, EEC, PSA, PAA (for FLA), and PVP, PSA, EEC, PAA (for PAC). (b) Correlations between calculated descriptors (top: API Diffusion coefficient, bottom: Coulomb contribution to the mixing energy) and amorphous stabilities (AI values for 40% drug-load) for FLA (left column) and PAC (right column). The dashed green lines are included as guide for the eye.