Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 9;10(3):127. doi: 10.3390/pharmaceutics10030127

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Ningalin B compounds which act as potent P-gp inhibitors, from references 45, 49, 50 and 51. (a) N3 [49]. (b) Compound 35. 1-(2-(4-(benzyloxy)-3-methoxyphenyl)-2-oxoethyl)-3,4-bis(3,4-dimethoxyphenyl)-1H-pyrrole-2,5-dione 1-(2-(2-bromo-5-methoxy-4-((3,4,5-trimethoxybenzyl)oxy) phenyl)-2-oxoethyl)-3,4-bis(3,4-dimethoxyphenyl)-1H-pyrrole-2,5-dione [50]. (c) Compound 23. 1-(2-(2-bromo-5-methoxy-4-((3,4,5-trimethoxybenzyl)oxy) phenyl)-2-oxoethyl)-3,4-bis(3,4-dimethoxyphenyl)-1H-pyrrole-2,5-dione [45]. (d) Compound 12. 1-(2-(4-(Benzyloxy)-5-bromo-2-(2-morpholinoethoxy)-phenyl)-2-oxoethyl)-3,4-bis(3,4-dimethoxy-phenyl)-1H-pyrrole2,5-dione [51].