Table 1.
Particle size, yield, drug loading content and % entrapment efficiency (EE) of risperidone PLA/PPAd prepared microspheres.
| Sample | Particle Size Range (μm) | Microparticles Yield (%) | Drug Loading (%) | Entrapment Efficiency (%) |
|---|---|---|---|---|
| PLA–risperidone | 3–17 | 78.34 ± 2.1 | 9.84 ± 1.7 | 36.51 ± 2.2 |
| PLA/PPAd 80/20-risperidone | 3–15 | 79.56 ± 2.1 | 11.24 ± 3.1 | 38.46 ± 3.1 |
| PLA/PPAd 60/40-risperidone | 3–14 | 82.37 ± 1.9 | 12.87 ± 3.0 | 41.87 ± 3.2 |
| PLA/PPAd 40/60-risperidone | 3–15 | 81.48 ± 2.9 | 14.21 ± 2.5 | 40.42 ± 2.6 |
| PLA/PPAd 20/80-risperidone | 2–10 | 80.54 ± 3.0 | 10.07 ± 3.1 | 39.17 ± 4.1 |
| PPAd-risperidone | 2–8 | 82.17 ± 2.0 | 12.49 ± 1.9 | 42.82 ± 3.0 |