Table 1.
Examples of different stabilizers used in screening studies for production of drug nanocrystals.
| Stabilizer | Drug | Reference |
|---|---|---|
| Methyl cellulose (MC), hydroxypropyl methylcellulose (HPMC), gelatin, sodium alginate, polyvinyl alcohol (PVA), polyvinyl pyrrolidone (PVP), polyethylene glycol (PEG), Tween 80, sodium deoxycholate, Pluronic F68, sodium dodecyl sulphate (SDS), sodium carboxymethyl cellulose (NaCMC), bovine serum albumin | Curcumin | [57] |
| Whey protein isolate, Poloxamer 188, SDS | Carvedilol | [58] |
| D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) | Loviride, itraconazole, cinnarizine, indomethacin, mebendazole, naproxen, phenytoin | [59] |
| SDS, sodium docusate, sodium cholate, Tween 80, Dehyquart® A-CA, Poloxamer 188, TPGS, PVA, HPMC | Amphotericin B, curcumin, hesperetin, ibuprofen, resveratrol, rutoside trihydrate | [60] |
| PVP, PVA-PEG, Poloxamer 188, TPGS, Tween 80, HPMC, hydroxyethyl cellulose (HEC), hydroxypropyl cellulose (HPC), MC, NaCMC, sodium alginate | Loviride, itraconazole, cinnarizine, griseofulvin, indomethacin, mebendazole, naproxen, phenylbutazone, phenytoin | [61] |
| Pluronic® F68, Pluronic® 17R4, Tetronic® 908, Tetronic® 1107, Pluronic® L64 | Indomethacin | [54] |
| Plantacare 810 UP, Plantacare 1200 UP, Plantacare 2000 UP | Curcumin | [62] |
| Poloxamer 407, Poloxamer 188, vitamin E-TPGS, lecithin, Poloxamer 188 + lecithin, Plantacare 2000 UP | Dexamethasone, ibuprofen, tacrolimus | [63] |