. 2018 Sep 12;10(3):158. doi: 10.3390/pharmaceutics10030158

Table 1.

Effective permeability and apparent permeability of PMX, PMX/DCK-NE, QCN, and QCN-NE.

Test Material	Effective Permeability Across an Artificial Membrane (P_e, ×10⁻⁶, cm/s)	Apparent Permeability Across a Caco-2 Cell Monolayer (P_app, ×10⁻⁶, cm/s)
PMX in water	6.03 ± 1.41	1.57 ± 0.749
PMX/DCK	15.3 ± 3.65 ***	11.9 ± 1.47 ***
PMX/DCK-NE	33.1 ± 0.739 ***^,###	15.8 ± 3.53 ***^,#
QCN in water	0.000± 0.000	0.550 ± 0.032
QCN in 0.3% NaCMC	1.20 ± 0.527 **	2.21 ± 0.533
QCN-NE	16.6 ± 0.621 ***^,$$$	8.46 ± 2.21 ***^,$$$

Values are expressed as mean ± standard deviation (n = 6). ** p < 0.01, *** p < 0.001 compared with PMX or QCN in water; ^# p < 0.05, ^### p < 0.001 compared with PMX/DCK; ^$$$ p < 0.001 compared with QCN in 0.3% NaCMC.