Table 3.
AUC values for mass flux and lag time obtained from the KTP permeation profiles of the gel and the suspension using three cells and two membranes (cellulose and Strat-M membranes) in two media at 37 °C.
Matrix of KTP | Permeation Parameters | Conditions | |||||
---|---|---|---|---|---|---|---|
Media pH: 5.6 | Media pH: 7.4 | ||||||
Cell A | Cell B | Cell C | Cell A | Cell B | Cell C | ||
Gel | Cellulose membrane | ||||||
Flux (mol/cm2 h) × 104 | 2.68 ± 0.08 | 2.53 ± 00.9 | 2.71 ± 0.01 | 2.54 ± 0.03 | 2.75 ± 0.08 | 2.77 ± 0.01 | |
Lag-time (h) | 0.04 | 0.013 | 0.007 | 0.12 | 0.107 | 0.119 | |
Strat-M membrane | |||||||
Flux (mol/cm2 h) × 104 | 2.07 ± 0.08 | 2.12 ± 0.08 | 2.10 ± 0.08 | 1.96 ± 0.03 | 2.00 ± 0.09 | 1.94 ± 0.01 | |
Lag-time (h) | 0.012 | 0.056 | 0.055 | 0.433 | 0.457 | 0.179 | |
Simple suspension | Cellulose membrane | ||||||
Flux (mol/cm2 h) × 104 | 2.82 ± 0.04 | 2.83 ± 0.10 | 2.81 ± 0.07 | 2.03 ± 0.12 | 2.07 ± 0.05 | 2.18 ± 0.07 | |
Lag-time (h) | 0.108 | 0.101 | 0.109 | 0.126 | 0.130 | 0.142 | |
Strat-M membrane | |||||||
Flux (mol/cm2 h) × 104 | 0.25 ± 0.03 | 0.27 ± 0.01 | 0.27 ± 0.01 | 0.18 ± 0.01 | 0.10 ± 0.02 | 0.10 ± 0.03 | |
Lag-time (h) | 0.298 | 0.221 | 0.225 | 0.324 | 0.329 | 0.382 |