Table 3.

Deposition in Healthy Subjects and Asthmatic and COPD Patients Following Inhalation of Four Actuations of the BDP/FF (100/6 μg) NEXThaler^® Radiolabeled Formulation

	Group
Variable	Healthy subjects, n = 10	Asthma patients, n = 9	COPD patients, n = 9
Lung deposition (% emitted dose)	55.2 ± 3.7 (50.5; 62)	56.2 ± 5.8 (45.3; 63.6)	54.9 ± 4.9 (48.5; 64.2)
Extrathoracic deposition (% emitted dose)	43.2 ± 4.2 (35.7; 48.8)	41.8 ± 5.6 (34.5; 53.7)	41.8 ± 4.8 (33.8; 46.9)
Amount exhaled (% emitted dose)	1.63 ± 0.72 (0.80; 3.00)	1.92 ± 1.55 (0.40; 5.80)	3.28 ± 1.56* (1.30; 5.40)
C/P	1.23 ± 0.19 (0.95; 1.54)	2.02 ± 0.59** (1.41; 3.27)	1.57 ± 0.29 (1.29; 2.03)
C/T	1.12 ± 0.11 (0.94; 1.27)	1.47 ± 0.19 (1.25; 1.80)	1.29 ± 0.13 (1.16; 1.48)
P/T	1.18 ± 0.06 (1.11; 1.29)	0.96 ± 0.13 (0.77; 1.11)	1.07 ± 0.07 (0.92; 1.17)
VAR (pixel counts)	0.0001 ± 0.0000 (0.0001; 0.0001)	0.0003 ± 0.0002*** (0.0001; 0.0008)	0.00018 ± 0.00007 (0.0001; 0.0003)

Results are presented as mean ± standard deviation (range).

^*p = 0.0116 versus healthy subjects.

^**p = 0.0002 versus healthy subjects.

^***p = 0.0029 versus healthy subjects.