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. 2018 Sep 27;10:103. doi: 10.1186/s13195-018-0432-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The topography of cortical thinning related to education in (a) PiB(−) svMCI and (b) PiB(−) SVaD. A negative relationship between years of education and cortical thickness was found in the bilateral dorsolateral frontal, left medial frontal, and parahippocampal areas in the PiB(−) SVaD group. q < 0.05 after false discovery rate correction. Adjusted for age, sex, intracranial volume, MMSE, hypertension, diabetes, hyperlipidemia, smoking, sqrtWMH, and sqrtLacune (model 3). MMSE Mini Mental State Examination, PiB Pittsburgh Compound B, svMCI Subcortical vascular mild cognitive impairment, sqrt Square root transformation, SVaD Subcortical vascular dementia, WMH White matter hyperintensities