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. 2018 Sep 27;18:263. doi: 10.1186/s12906-018-2320-8

Fig. 3.

Fig. 3

Effect of ES on the gene expression of (a) IL-1β, (b) IL-8 and (c) TNF-α in P. acnes-induced THP-1 cells. The expression level of mRNA was determined using a Real-time PCR. THP-1 cells were pre-treated with 0.1, 1 and 10 μg/ml of ES for 4 hrs incubation and then stimulated with P. acnes for 18 hrs incubation. Values represent mean ± S.E.M. Data were analyzed by Tukey post hoc test ( * p < 0.05 versus control and ** p < 0.05 versus P.acnes alone)